I-Mebhydrolin napadisylate (i-mehydraline) iyisidakamizwa se-antihistamine, eyaziwa nangokuthi isizukulwane sokuqala se-antihistamine H1 receptor antagonist. Umsebenzi wayo oyinhloko ukuvimbela ukukhululwa kwe-histamine emzimbeni, ngaleyo ndlela kuncishiswe izimpawu ezibangelwa ukungezwani komzimba, njengokuthimula, ikhala eligijimayo, amehlo anamanzi, ukulunywa, njll.